Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

XBP-1S monoclonal antibody (8F6.11)

 
ENZ-ABS255-0100 100 µg 378.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:X-box binding protein 1, Tax-responsive element-binding protein 5, TREB5, XBP2
 
Host:Mouse
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human XBP-1, spliced isoform XBP1(S).
 
UniProt ID:P17861
 
Species reactivity:Human, Mouse
 
Applications:ELISA, ICC, IP, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (1:100)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~60kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of misfolded proteins in the endoplasmic reticulum (ER). XBP-1 mRNA is spliced by IRE1p under ER stress, resulting in a 371 amino acid protein (XBP-1s) which is translocated to the nucleus where it binds to the regulatory elements of downstream genes. XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones grp78 and grp94.
 
ENZ-ABS255 WB
Western blot analysis of XBP-1S mAb (8F6.11) (Prod. No. ENZ-ABS255): Lane 1: MW markers, Lane 2: mock-transfected CHO cell, Lane 3: XBP-1S (spliced isoform)-transfected CHO cell. The observed molecular weight of XBP-1S is ~60 kDa (calculated MW: 40 kDa).
Please mouse over
ENZ-ABS255 WB

Related Products

Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) 

ELISA, IHC, WB | Print as PDF
 
ADI-SAB-300-J 1 ml 118.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
XBP
By biological activity:
XBP Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,