TMRE (ultra pure)

Mitochondria dye



ENZ-52309	25 mg	133.00 USD

Positively charged rhodamine dyes (such as rhodamine esters and rosamines) are selectively localized in mitochondria, thus they are widely used for labeling mitochondria of live cells. Like JC-1,TMRE is widely used for measuring mitochondrial membrane potential, in addition to selectively staining mitochondria. Real-time imaging of mitochondrial membrane potential in individual cardiomyocytes within perfused rat hearts has been demonstrated with this dye, using 2-photon laser-scanning microscopy. Wavelength Maxima: Excitation 549nm, Emission 574nm

Product Specification

Alternative Name:	Tetramethylrhodamine ethyl ester perchlorate

Formula:	C₂₆H₂₇ClN₂O₇

MW:	515.0

Purity:	≥95% (HPLC)

CAS:	115532-52-0

Solubility:	Soluble in DMSO.

Long Term Storage:	-20°C

Use/Stability:	Stable for at least one year after receipt when stored as recommended.

Hazard:	HARMFUL. IRRITANT.

Handling:	Keep cool and dry. Protect from light.

Background / Technical Information:	This product is a member of the CELLestial^® product line, reagents and assay kits comprising fluorescent molecular probes that have been extensively benchmarked for live cell analysis applications. CELLestial^® reagents and kits are optimal for use in demanding imaging applications, such as confocal microscopy, flow cytometry and HCS, where consistency and reproducibility are required.

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Product Literature References

The mitochondrial membrane potential and Ca2+ oscillations in smooth muscle: S. Chalmers & J.G. McCarron; J. Cell Sci. 121, 75 (2008), Abstract;

Real-time 2-photon imaging of mitochondrial function in perfused rat hearts subjected to ischemia/reperfusion: M. Matsumoto-Ida, et al.; Circulation 114, 1497 (2006), Abstract;