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H-Ficolin (human) monoclonal antibody (FCN334) (biotin conjugate)

 
BPD-RIG-334-01B-01 100 µg 632.00 USD
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Product Specification

Alternative Name:Hakata antigen, Ficolin-3
 
Clone:FCN334
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant human H-ficolin.
 
UniProt ID:O75636
 
Species reactivity:Human
 
Applications:ELISA
 
Application Notes:Detects a band of ~35kDa (monomer) by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.14M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35kDa protein chains associated in triplet subunits, which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
 

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