NGAL (also known as Lipocalin-2 or Neutrophil Gelatinase-associated Lipocalin) is a small, ~25kDa secreted protein expressed in epithelial tissues throughout the body.
Normothermic machine perfusion of ischaemically damaged porcine kidneys with autologous, allogeneic porcine and human red blood cells: M.B.F. Pool, et al.; PLoS One 15, e0229566 (2020), Abstract; Full Text
Carbamylated erythropoietin-FC fusion protein and recombinant human erythropoietin during porcine kidney ischemia/reperfusion injury: Š. Matějková, et al.; Intensive Care Med. 39, 497 (2013), Abstract;
Neutrophil gelatinase-associated lipocalin (NGAL) levels in response to unilateral renal ischaemia in a novel pilot two-kidney porcine model: J.L. Silberstein, et al.; BJU Int. 112, 517 (2013), Abstract;
Early outcome in renal transplantation from large donors to small and size-matched recipients - a porcine experimental model: K. Ravlo, et al.; Pediatr. Transplant. 16, 599 (2012), Abstract;
Early urinary biomarkers of warm and cold ischemic injury in an experimental kidney model: S.A. Hosgood, et al.; J. Surg. Res. 174, e85 (2012), Abstract;
NGAL excretion is higher from the healthy side than from the injured side in unilateral acute kidney injury: S.S. Pedersen, et al.; Scand J. Clin. Lab Invest. 72, 510 (2012), Abstract;
Protective effect of low potassium dextran solution on acute kidney injury following acute lung injury induced by oleic acid in piglets: R.P. Wu, et al.; Chin. Med. J. (Engl.) 125, 3093 (2012), Abstract;
Circulating AST, H-FABP, and NGAL are early and accurate biomarkers of graft injury and dysfunction in a preclinical model of kidney transplantation: I. Jochmans, et al.; Ann. Surg. 254, 784--91; discussion 791-2 (2011), Abstract;
Neutrophil gelatinase-associated lipocalin, a new biomarker candidate in perfusate of machine-perfused kidneys: a porcine pilot experiment: I. Jochmans, et al.; Transplant Proc. 43, 3486 (2011), Abstract;
General Literature References
Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics: D. Burt, et al.; Drug Chem. Toxicol. 37, 204 (2014), Abstract;
Ultra sensitive (1.279 pg/ml) ELISA kit, enabling reduced input sample and matrix interference, for the quantification of KIM-1, an early biomarker for kidney injury or disease.
