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Amyloid β-peptide (human) monoclonal antibody (16E9)

 
BPD-HYB-310-04-02 200 µg 388.00 USD
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Product Specification

Clone:16E9
 
Host:Mouse
 
Isotype:Mouse IgG2a
 
Immunogen:Synthetic peptide corresponding to aa 5-16 of human amyloid β-peptide.
 
UniProt ID:P05067
 
Species reactivity:Human
 
Applications:ELISA
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Beta-amyloid/Abeta is the major protein component of neurofibrillary tangles and senile plaques, major neuropathological hallmarks of Alzheimer's disease (AD). Abeta occurs in two predominant forms with different COOH-termini, Abeta40 and Abeta42. Abeta is generated by proteolytic cleavage of the amyloid precursor protein (APP) at two sites by distinct secretases, the beta-site secretase BACE, and the multi-subunit gamma-secretase composed of presenilin, nicastrin, Aph-1, and Pen-2.
 

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