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Clostridium tetani toxoid monoclonal antibody (6E7)

 
BPD-HYB-278-17-02 200 µg 632.00 USD
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Product Specification

Clone:6E7
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Tetanus toxoid.
 
UniProt ID:P04958
 
Species reactivity:Clostridium tetani
 
Applications:ELISA
 
Application Notes:Detects a band of ~150kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Clostridium tetani is a Gram-positive, motile bacterium found in soil and animal feces. Toxigenic strains of C. tetani contain a plasmid encoding the potent exotoxin which causes tetanus (lockjaw). The toxin is synthesized as a single 150kDa protein chain which is cleaved ("nicked") into a 100kDa heavy chain (fragment B) and a 50kDa light chain (fragment A) connected by a disulfide bridge. Tetanus toxoid is produced by prolonged incubation of the toxin with formaldehyde and lysine, and is often used as a carrier for compounds of poor immunogenicity.
 

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