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Surfactant protein D (human) monoclonal antibody (16C11)

BPD-HYB-245-02-02 200 µg 396.00 USD
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Product Specification

Alternative Name:Pulmonary surfactant-associated protein D, SP-D, PSP-D
Immunogen:Recombinant human neck CRD SP-D.
UniProt ID:P35247
Species reactivity:Human
Applications:ELISA, IHC, WB
Purity Detail:Protein A/G-affinity purified.
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
Shipping:Blue Ice Not Frozen
Short Term Storage:+4°C
Scientific Background:Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins, members of which possess an overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-D, and the serum proteins mannan-binding protein, conglutinin, and collectin-43, all of which bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals.
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Figure 1: Immunohistochemical analysis of paraffin-embedded human lung tissue using Surfactant protein A (human), mAb (6F10).
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Figure 2: Immunohistochemical analysis of paraffin-embedded human lung tissue using Surfactant protein D (human), mAb (16C11).
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