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Surfactant protein A (human) monoclonal antibody (6F10)

 
BPD-HYB-238-04-02 200 µg 388.00 USD
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Product Specification

Alternative Name:Pulmonary surfactant-associated protein A, SP-A
 
Clone:6F10
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Purified human native SP-A from bronchioaveolar lavage from proteinosis patients.
 
UniProt ID:Q8IWL2
 
Species reactivity:Human
 
Applications:ELISA, IHC, WB
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins, members of which possess an overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-D, and the serum proteins mannan-binding protein, conglutinin, and collectin-43, all of which bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals.
 
HYB 238-04  1  web
Figure 1: Immunohistochemical analysis of paraffin-embedded human lung tissue using Surfactant protein A (human), mAb (6F10).
HYB 238-04  2  web
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung tissue using Surfactant protein A (human), mAb (6F10).
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HYB 238-04  1  web HYB 238-04  2  web

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