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Antitrypsin α1 (native, denat.) (human) monoclonal antibody (3B7)

 
BPD-HYB-191-01-02 200 µg 388.00 USD
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Product Specification

Alternative Name:a-1 AT
 
Clone:3B7
 
Host:Mouse
 
Isotype:IgG2aκ
 
Immunogen:Human α1-AT from plasma.
 
UniProt ID:P07477
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~51kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:The serum glycoprotein alpha1-antitrypsin (alpha1- AT) is a typical member of the serpin family (serine protease inhibitors), and an inhibitor of trypsin. Alpha1- AT is synthesized in the liver as a single polypeptide chain of approximately 51kDa. It exhibits a marked degree of genetic polymorphism due to the presence of over 20 different alleles. Individuals homozygous for alpha1- AT deficiency are predisposed to pulmonary emphysema and hepatic cirrhosis.
 

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