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GLP-1 (7-36, amide) monoclonal antibody (4F3) (biotin conjugate)

 
BPD-HYB-147-12B-005 50 µg 428.00 USD
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Product Specification

Alternative Name:Glucagon like peptide 1
 
Clone:4F3
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Synthetic peptide corresponding to aa 7-36 amide of GLP-1 coupled to carrier.
 
UniProt ID:P01275
 
Species reactivity:Mammalian
 
Applications:ELISA
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.14mM sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
 
Glucagon-like peptide-1 web
Figure: Schematic glucagon-like peptide-1 (GLP-1) showing active, extended and metabolite forms along with select GLP-1 monoclonal antibodies.
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Glucagon-like peptide-1 web

Product Literature References

Role of fatty acid transport protein 4 in oleic acid-induced glucagon-like peptide-1 secretion from murine intestinal L cells: M. Poreba, et al.; Am. J. Physiol. Endocrinol. Metab. 303, E899 (2012), Application(s): Radioimmunoassay of murine GLUTag cells , Abstract; Full Text

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