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Tetranectin (human) monoclonal antibody (10E3)

 
BPD-HYB-130-13-02 200 µg 388.00 USD
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Product Specification

Alternative Name:TN
 
Clone:10E3
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Purified human tetranectin from citrate plasma. Boosted before fusion with recombinant tetranectin produced in E. coli.
 
UniProt ID:P05452
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~20kDa (monomer) by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Tetranectin (TN) is a C-type lectin serum and tissue protein which binds to Ca++. It is a homotrimer of monomers, each with a mass of 20kDa, with plasma or serum concentrations of approximately 10 mg/L. In vitro, TN can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. TN is best known as a prognostic marker in ovarian cancer.
 

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