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Corynebacterium (Diphtheria toxoid) monoclonal antibody (17.6B9)

 
BPD-HYB-123-05-02 200 µg 571.00 USD
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Product Specification

Alternative Name:Diphtheria toxoid, Corynebacterium diphtheriae
 
Clone:17.6B9
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Purified Diphtheria toxoid from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation.
 
Species reactivity:Corynebacterium
 
Applications:ELISA
 
Application Notes:Detects a band of ~62kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphteriae infects the epithelial cells of the upper respiratory tract, which then secrete a potent toxin absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21kDa and a B chain of 40kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action.
 

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Corynebacterium diphtheriae
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