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Thrombin (human) monoclonal antibody (5G9)

 
BPD-HYB-109-04-02 200 µg 388.00 USD
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Product Specification

Alternative Name:Coagulation factor II receptor-like 1
 
Clone:5G9
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Human thrombin from activated plasma.
 
UniProt ID:P00734
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~37kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Thrombin is the active enzyme that splits fibrinogen into fibrin during the final stage of blood coagulation. It is generated from its circulating inactive precursor, prothrombin, by the action of factor Xa aided by factor Va, phospholipid and calcium ions. Thrombin is a glycoprotein formed by a 6kDa alpha chain, linked by a disulfide bridge to a 31kDa beta chain which carries the serine protease catalytic site.
 

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