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von Willebrand factor (human) monoclonal antibody (5E7)

 
BPD-HYB-060-01-02 200 µg 388.00 USD
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Product Specification

Alternative Name:F8VWF, vWF
 
Clone:5E7
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Human factor VIII complex from plasma.
 
UniProt ID:P04275
 
Species reactivity:Human
 
Applications:ELISA
 
Application Notes:Detects a band of ~225kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), thereby stabilizing the latter and playing an important role in the normal primary haemostasis.
 

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