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Complement component C5a (human) monoclonal antibody (C17/5)

 
BPD-GAU-025-05-02 200 µg 632.00 USD
 
BPD-GAU-025-05-1 1 mg 2,834.00 USD
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Product Specification

Clone:C17/5
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Purified human complement component C5a.
 
UniProt ID:P01031
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 10mM phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Long Term Storage:+4°C
 
Scientific Background:Complement C5a is generated in the circulation by the activation of complement. It is a so-called anaphylatoxin of 74 amino-acid residues generated by the action of C5 convertase, which cleaves C5 into C5a and C5b. It is rapidly inactivated by serum carboxypeptidase B, which removes the C-terminal arginine residue generating C5a(desArg).
 

General Literature References

A sensitive enzyme immunoassay for the quantitation of human C5a/C5a(desArg) anaphylatoxin using a monoclonal antibody with specificity for a neoepitope: M. Oppermann, et al.; Complement Inflamm. 8, 13 (1991), Abstract;

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