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GLP-1 (9-37, 9-36, amide, free NT) monoclonal antibody (53)

 
BPD-ABS-044-53-02 200 µg 632.00 USD
 
BPD-ABS-044-53-1 1 mg 2,834.00 USD
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Product Specification

Alternative Name:Glucagon like peptide 1
 
Clone:53
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Synthetic peptide corresponding to aa 9-18 of GLP-1.
 
UniProt ID:P01275
 
Species reactivity:Mammalian
 
Applications:ELISA, WB
 
Purity Detail:Protein A-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Glucagon-like peptide-1 (9-36) amide and GLP-1 (9-37) are the forms of GLP-1 which result from rapid degradation of the active forms of the peptide (GLP-1 (7-36) amide and GLP-1 (7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
 
Glucagon-like peptide-1 web
Figure: Schematic glucagon-like peptide-1 (GLP-1) showing active, extended and metabolite forms along with select GLP-1 monoclonal antibodies.
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Glucagon-like peptide-1 web

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