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NGAL (mouse) monoclonal antibody (10)

 
BPD-ABS-043-10-02 200 µg 632.00 USD
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Product Specification

Alternative Name:Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin, Oncogene 24p3
 
Clone:10
 
Host:Rat
 
Isotype:IgG1κ
 
Immunogen:Recombinant mouse NGAL.
 
UniProt ID:P11672
 
Species reactivity:Mouse
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~25kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Mouse neutrophil gelatinase-associated lipocalin (NGAL; also lipocalin 2, 24p3, SIP24, uterocalin and siderocalin) belongs to the lipocalin family of proteins which bind and transport small lipophilic molecules. Following research showing 24p3 dramatically upregulated in kidney cell cultures infected with SV40, it was subsequently identified as a lipocalin. Unlike human NGAL, mouse NGAL is an acute phase protein upregulated in the liver, but like its mammalian homologues, it is upregulated and secreted by the kidney in response to ischemic or nephrotoxic injury. It is also upregulated in the involuting uterus and mammary gland.
 

General Literature References

Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics: D. Burt, et al.; Drug Chem. Toxicol. 37, 204 (2014), Abstract;

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