Product Details
| Alternative Name: | Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin, Neutrophil lipocalin |
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| Clone: | 32 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Recombinant rat NGAL precursor. |
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| UniProt ID: | P30152 |
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| GenBank ID: | 170496 |
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| Species reactivity: | Rat
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| Crossreactivity: | Does not cross-react with human, pig, dog or mouse. |
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| Applications: | ELISA
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.14M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Rat lipocalin-2 is also called rat NGAL, as it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL). Rat NGAL is a 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including cells of the renal proximal tubules. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is upregulated in a variety of pathological situations including infection, inflammation, ischemia-reperfusion and in certain adenocarcinomas. |
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| Regulatory Status: | RUO - Research Use Only |
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General Literature References
Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics: D. Burt, et al.; Drug Chem. Toxicol.
37, 204 (2014),
Abstract;
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