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United States 

NGAL (rat), mAb (15)

 
BPD-ABS-039-15-02 200 µg 690.00 USD
 
BPD-ABS-039-15-1 1 mg 3,100.00 USD
 

Product Specification

Alternative Name:Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin
 
Clone:15
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant rat NGAL precursor.
 
UniProt ID:P30152
 
Application:ELISA (1:10,000)
Optimal conditions must be determined individually for each application.
 
Specificity:Recognizes rat NGAL. Detects a band of ~25kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Short Term Storage:+4°C
 
Long Term Storage:+4°C
 
Miscellaneous/General:Rat lipocalin-2 is also called rat NGAL, as it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL). Rat NGAL is a 25kDa α2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including cells of the renal proximal tubules. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is upregulated in a variety of pathological situations including infection, inflammation, ischemia-reperfusion and in certain adenocarcinomas.
 

General Literature References

Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics: D. Burt, et al.; Drug Chem. Toxicol. 37, 204 (2014), Abstract;
Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury: J. Mishra, et al.; J. Am. Soc. Nephrol. 14, 2534 (2003), Abstract;

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