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GLP-1 (7-37, 7-36, amide, free NT) monoclonal antibody (4)

 
BPD-ABS-033-04-02 200 µg 632.00 USD
 
BPD-ABS-033-04-1 1 mg 2,834.00 USD
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Product Specification

Alternative Name:Glucagon like peptide 1
 
Clone:4
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Synthetic peptide corresponding to aa 7-17 of GLP-1.
 
UniProt ID:P01275
 
Species reactivity:Mammalian
 
Crossreactivity:Shows <0.2% cross-reactivity with GLP-1(1-37), GLP-1(9-36)amide, glucagon, human GIP and exendin-4. Cross-reacts approximately 1% with human GLP-2.
 
Applications:ELISA, IHC
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Not recommended for use in sandwich ELISA.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Glucagon-like peptide 1 (7-36) amide (GLP-1 (7-36) amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
 
Glucagon-like peptide-1 web
Schematic glucagon-like peptide-1 (GLP-1) showing active, extended and metabolite forms along with select GLP-1 monoclonal antibodies.
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Glucagon-like peptide-1 web

Product Literature References

An ultrasensitive method for the quantitation of active and inactive GLP-1 in human plasma via immunoaffinity LC-MS/MS.: D. Chappell, et al.; Bioanalysis 6, 33 (2014), Application(s): LC-MS/MS assay of human plasma samples, Abstract;

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