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Vasoactive intestinal peptide monoclonal antibody (2)

 
BPD-ABS-023-02-1 1 mg 2,591.00 USD
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Product Specification

Alternative Name:VIP
 
Clone:2
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Vasoactive intestinal peptide.
 
UniProt ID:P01282
 
Species reactivity:Human, Rat
Bovine, Porcine
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~3kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Vasoactive intestinal peptide (VIP) is a 28-amino-acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in man, ox, pig and rat. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) lead to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in man or peptide histidine-serine (PHI) in pigs or rats, present in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP).
 

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