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Complement component C9 (human) monoclonal antibody (22)

 
BPD-ABS-004-22-02 200 µg 388.00 USD
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Product Specification

Alternative Name:C9 esterase
 
Clone:22
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Human complement factor C9.
 
UniProt ID:P02748
 
Species reactivity:Human
 
Applications:ELISA, IF, IHC, WB
 
Application Notes:Detects a band of ~71kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 binds the C5b8 complex on membranes and has the unique function of forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes; secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/ml, and the level is upregulated from hepatocytes by IFN-γ.
 
BPD-ABS-004-22 1 IF
IF staining of tonsil tissue with BPD-ABS-004-22. Follicular dendritic cell network stained strongly in germinal centers of tonsil tissue. Dilution: 1:75.
BPD-ABS-004-22 2 IF
IF staining of human kidney with BPD-ABS-004-22. Plasma of veins are strongly stained. Dilution: 1:75.
BPD-ABS-004-22 3 IHC
IHC staining of human liver with BPD-ABS-004-22. Plasma of portal veins are strongly stained. Dilution: 1:100.
BPD-ABS-004-22 4 IHC
IHC staining of tonsil tissue with BPD-ABS-004-22. Follicular dendritic cell network stained strongly in germinal centers of tonsil tissue. Also moderate staining were observed from plasma of veins. Dilution: 1:100.
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BPD-ABS-004-22 1 IF BPD-ABS-004-22 2 IF BPD-ABS-004-22 3 IHC BPD-ABS-004-22 4 IHC

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