Cytochrome P450 2B6 (human), pAb



BML-CR3290-0025	25 µl	90.00 USD

BML-CR3290-0100	100 µl	312.00 USD

Phenobarbital is well established as a potent inducer of cytochrome P-450 2B (CYP2B) expression, and work by different groups has shown that AP-1 might play a role in the induction process, and that insulin is able to supress the effect of phenobarbital. Human CYP2B6 appears to be the primary enzyme involved in the N-demethylation of S-mephenytoin and may contribute to the hepatic metabolism of toluene to benzyl alcohol.

Product Specification

Alternative Name:	CYP2B6

Immunogen:	Synthetic peptide corresponding to aa 265-276 of human liver CYP2B6.

Source/Host:	From rabbit.

Specificity:	Recognizes human wild-type CYP2B6.1 and all known variants of CYP2B6.

Application:	Immunohistochemistry Western Blot

Long Term Storage:	-20°C

Background / Technical Information:	Please click here for the comprehensive product datasheet.