ISG15 activating enzyme E1 (human), (recombinant) (His-tag)

Purity Detail:	Purified by Ni-affinity chromatography.

Purity:	>95%

Source/Host:	Produced in E. coli. Human ISG15 E1 is fused at the C-terminus to a His-tag.

Application:	Activation of ISG15 for ISGylation of specific proteins in presence of dedicated E2 conjugating/E3 ligase enzymes. ISGylation pathway studies. Test proteins for ISG15 E3 ligase activity. Test proteins as potential targets for ISG15 modification.

Long Term Storage:	-80°C

Miscellaneous/General:	The interferon (IFN)-a/ß-induced ISG15 E1 activating enzyme, also known as known as Ube1L, is a single-subunit, ATP dependent enzyme that facilitates conjugation of ISG15 to cellular proteins via the ISGylation pathway.

Background / Technical Information:	Please click here for the comprehensive product datasheet.