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[K27R]Ubiquitin (human), (recombinant) (untagged)

BML-UW0255-0001 1 mg 94.00 USD
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Product Specification

MW:~8.6 kDa
Source:Produced in E. coli.
UniProt ID:P0CG47 (UBB), P0CG48 (UBC), P62979 (RPS27A), P62987 (UBA52)
Purity:≥95% (SDS-PAGE) (SDS-PAGE)
Purity Detail:Purified by perchloric acid treatment of a soluble lysate, followed by gradient elution from a cation exchange column.
Appearance:White solid.
Application Notes:For production of poly-ubiquitin chains via all lysines except lysine27.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:[K27R]Ubiquitin, in which Lys27 has been mutated to Arg, is unable to form poly-ubiquitin chains via Lys27 linkages. The ability to form an active thioester at the C-terminus is preserved, allowing [K27R]ubiquitin to be transferred to the lysines of substrate proteins.

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For Research Use Only. Not for use in diagnostic procedures.
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