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[K6R]Ubiquitin (human), (recombinant) (untagged)

 
BML-UW0245-0001 1 mg 89.00 USD
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Product Specification

MW:~8.6 kDa
 
Source:Produced in E. coli.
 
UniProt ID:P0CG47 (UBB), P0CG48 (UBC), P62979 (RPS27A), P62987 (UBA52)
 
Formulation:Lyophilized.
 
Purity:≥95% (SDS-PAGE) (SDS-PAGE)
 
Purity Detail:Purified by perchloric acid treatment of a soluble lysate, followed by gradient elution from a cation exchange column.
 
Appearance:White solid.
 
Application Notes:Uses:
1. Production of proteins modified by poly-ubiquitin chains, where ubiquitin can be linked via all lysines except Lys6.
2. Investigation of the formation and/or function of specific proteins modified by poly-ubiquitin chains, where ubiquitin can be linked via all lysines except Lys6.
3. Study of the production and/or role of poly-ubiquitin chains linked via all lysines except Lys6.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Ubiquitin, in which Lys6has been mutated to Arg, is unable to form poly-ubiquitin chains via Lys6 linkages. The ability to form an active thioester at the C-terminus is preserved, allowing [K6R]ubiquitin to be transferred to the lysines of substrate proteins.
 

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For Research Use Only. Not for use in diagnostic procedures.
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