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14-3-3τ/θ monoclonal antibody (3B9)

 
BML-TG1914-0100 100 µg 300.00 USD
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Product Specification

Clone:3B9
 
Host:Mouse
 
Isotype:IgG
 
Immunogen:Recombinant full length mouse 14-3-3θ.
 
UniProt ID:P68254 (human)
 
Species reactivity:Human, Mouse, Rat
Bovine
 
Applications:ELISA, WB
 
Purity Detail:Purifed.
 
Formulation:Liquid. In PBS containing 3 mM sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:14-3-3 proteins are phosphoserine- and phosphothreonine-binding proteins, and as a family are known to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation state and stability, transcription, metabolism, and malignant transformation. 14-3-3τ/θ (τ in humans, θ in mice) interaction with CDC25c regulates entry into the cell cycle and apoptosis can be prevented following interaction with Bad. 14-3-3 τ/θ (τ in humans, θ in mice) has been shown to be present in testis and 14-3-3τ mRNA is up-regulated in amyotrophic lateral sclerosis spinal cord.
 

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