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PI 3K-SH2-OMT

PI3 kinase inhibitor
 
BML-ST425-0500 0.5 mg 157.00 USD
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This unique SH2 domain ligand is derived from the sequence flanking Tyr751 of the PDGF receptor. It inhibits the PI 3-kinase p85 C-terminal SH2 domain (IC50=14.2 µM). It contains the nonhydrolyzable phosphotyrosine mimetic L-O-(2-malonyl)tyrosine (OMT) and is provided as the trimethyl ester for greater cell permeability.

Product Specification

Sequence:Ac-Asp-Tyr(2-malonyl)-Val-Pro-Met-Leu-NH2 trimethyl ester
 
MW:922.1
 
Formulation:Lyophilized.
 
Purity:≥98% (TLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (0.5 mg/ml) or ethanol (0.3 mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 

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