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Thioetheramide-phosphorylcholine

Phospholipase inhibitor
 
BML-ST325-0005 5 mg Inquire for pricing
 
BML-ST325-0025 25 mg 355.00 USD
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Replaces Prod. #: ALX-300-142

A potent substrate analog inhibitor of snake venom PLA2 (IC50=2 µM). It inhibits human recombinant sPLA2 (IC50=0.9 µM) selectively over cPLA2.

Product Specification

Alternative Name:1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine
 
Formula:C40H83N2O5PS
 
MW:735.6
 
CAS:116457-99-9
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO, 100% ethanol or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
 
Handling:Protect from moisture.
 
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Product Literature References

Secretory phospholipase A2 inhibitors and calmodulin antagonists as inhibitors of cytosolic phospholipase A2: W.C. Hope, et al.; Agents Actions 39, C39 (1993), Abstract;
The interaction of phospholipase A2 with phospholipid analogues and inhibitors: L. Yu, et al.; J. Biol. Chem. 265, 2657 (1990), Abstract;

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