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Z36

Bcl-XL inhibitor
 
BML-ST200-0005 5 mg 114.00 USD
 
BML-ST200-0025 25 mg 379.00 USD
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Novel inhibitor of Bcl-XL that induces autophagic cell death in HeLa cells. The first small molecule inhibitor of Bcl-XL that induces autophagic cancer cell death independent of apoptosis and is, thus, an important new tool for studying the cellular regulation of autophagy and apoptosis.

Product Specification

Alternative Name:(Z)-5-Fluoro-1-(3'-dimethylamino)propyl-3-[(5'-methoxyindol-3-ylidene)methyl]-indolin-2-one
 
Formula:C23H24FN3O2
 
MW:393.5
 
Purity:≥98% (TLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (>25mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
BML-ST200 structure
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BML-ST200 structure

Product Literature References

A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in HeLa cells: J. Lin, et al.; Autophagy 5, 314 (2009), Abstract;

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