Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

FTY-720 . HCl

S1P receptor ligand
BML-SL233-0005 5 mg 76.00 USD
BML-SL233-0025 25 mg 311.00 USD
Do you need bulk/larger quantities?
Replaces Prod. #: ALX-420-043

Novel immune modulator that alters migration and homing of lymphocytes. Acts as a potent agonist of sphingosine 1-phosphate receptors (S1P) after phosphorylation by sphingosine kinase. Also inhibits cytosolic phospholipase A2 independently of sphingosine 1-phosphate receptors.

Product Specification

Alternative Name:2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol . HCl, Fingolimod . HCl
Formula:C19H33NO2 . HCl
MW:307.4 . 36.5
Purity:≥98% (HPLC)
Identity:Determined by NMR.
Appearance:White solid.
Solubility:Soluble in DMSO (10mg/ml), 100% ethanol or dimethyl formamide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
420-043 01
Please mouse over
420-043 01

Product Literature References

The Sphingosine 1-Phosphate Receptor Agonist FTY720 Potently Inhibits Regulatory T Cell Proliferation In Vitro and In Vivo: A.M. Wolf, et al.; J. Immunol. 183, 3751 (2009), Abstract;
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia: P. Neviani, et al.; J. Clin. Invest. 117, 2408 (2007), Abstract; Full Text
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors: S.G. Payne, et al.; Blood 109, 1077 (2007), Abstract;
The immune modulator FTY720 targets sphingosine 1-phosphate receptors: V. Brinkmann, et al.; J. Biol. Chem. 277, 21453 (2002), Abstract; Full Text

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Product Flyers
Exclusive Sphingosine Kinase 1 Inhibitor
Exclusive Sphingosine Kinase 1 Inhibitor
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,