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BML-241

S1P receptor ligand
 
BML-SL227-0005 5 mg 81.00 USD
 
BML-SL227-0025 25 mg 285.00 USD
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BML-241 is a sphingosine-1-phosphate receptor antagonist. It blocks the S1P induced rapid Ca2+ increase in HeLa cells overexpressing S1P3 (EDG3) receptors (37% inhibition at 10 µM).

Product Specification

Alternative Name:S1P Receptor Antagonist, 2(R,S)-Undecylthiazolidine-4(R)-carboxylic acid
 
Formula:C15H29NO2S
 
MW:287.5
 
CAS:298186-80-8
 
Purity:≥98%
 
Appearance:White solid
 
Solubility:Soluble in DMSO (2mg/ml with warming), ethanol (1mg/ml with warming), or DMF (3mg/ml with warming).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store solutions at -20°C for up to 3 months.
 
BML-SL227 structure
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BML-SL227 structure

Product Literature References

Development of Novel EDG3 Antagonists Using a 3D Database Search and Their Structure−Activity Relationships: Y. Koide, et al. ; J. Med. Chem. 45, 4629 (2002), Full Text

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