Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 


Induces release of Ca2+ from intracellular stores
BML-SL141-0010 10 mg 301.00 USD
Do you need bulk/larger quantities?
Sphingosylphosphorylcholine induces release of Ca2+ from intracellular stores via an IP3 independent pathway in permeabilized pancreatic acinar cells. It is an extremely potent mitogen in numerous cell types and induces neurite outgrowth in mouse neuroblastoma cells. It rapidly activates transcription factor AP-14 and transiently activates MAP kinase.

Product Specification

Purity:≥98% (HPLC)
Appearance:Waxy solid.
Solubility:Soluble in water (>50 mg/ml) or ethanol (>50 mg/ml).
Long Term Storage:-20°C
BML-SL141 structure
Please mouse over
BML-SL141 structure

Product Literature References

A novel trigger for cholesterol-dependent smooth muscle contraction mediated by the sphingosylphosphorylcholine-Rho-kinase pathway in the rat basilar artery: a mechanistic role for lipid rafts: S. Shirao, et al.; J. Cereb. Blood Flow Metab. 35, 835 (2015), Application(s): Injection, Abstract;
Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1: A. Berger, et al.; Proc. Natl. Acad. Sci. U. S. A. 92, 5885 (1995), Abstract; Full Text
Sphingosylphosphorylcholine activation of mitogen-activated protein kinase in Swiss 3T3 cells requires protein kinase C and a pertussis toxin-sensitive G protein: T. Seufferlein, et al.; J. Biol. Chem. 270, 24334 (1995), Abstract; Full Text
Metabolism and neurite promoting effect of exogenous sphingosylphosphocholine in cultured murine neuroblastoma cells: E. Sugiyama, et al.; J. Biochem. 113, 467 (1993), Abstract;
Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts: N. N. Desai, et al.; J. Cell. Biol. 121, 1385 (1993), Abstract; Full Text
Sphingosine metabolism induces Ca2+ oscillations in rat pancreatic acinar cells: D.I. Yule, et al.; J. Biol. Chem. 268, 12353 (1993), Abstract;

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Product Flyers
Exclusive Sphingosine Kinase 1 Inhibitor
Exclusive Sphingosine Kinase 1 Inhibitor
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2018 Enzo Life Sciences, Inc.,