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Procaspase-7 (truncated) (human), (recombinant)

 
BML-SE700-0100 100 µg 455.00 USD
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The purified protein (34 kDa) is highly activatable by treatment with particular active caspases (caspase-1 >> caspase-10 > caspase-8), while having low inherent activity, and little or no contamination with processed caspase-7. The selectivity of the activation process may provide the basis for assays which 1) distinguish death-receptor initiated apoptosis from that initiated via the mitochondrial/apoptosome pathway or 2) detect active caspase-1.

Product Specification

MW:34 kDa
 
Source:Produced in E. coli. Truncated human procaspase-7 (aa 24-303).
 
UniProt ID:P55210
 
GenBank ID:U40281
 
Formulation:Liquid. In 50mM HEPES, pH 7.4, 100mM NaCl, 0.5% CHAPS, 10mM DTT, 1mM EDTA, 10% glycerol .
 
Purity Detail:Partially purified by single-step affinity chromatography and gel filtration.
 
Activity:Recombinant procaspase-7, expressed in E. coli without the N-terminal prodomain, is relatively slow to autoactivate. It can be activated in vitro by treatment with active recombinant caspases.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 

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For Research Use Only. Not for use in diagnostic procedures.
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