RAP (human), (recombinant) (GST-tag)



BML-SE552-0100	100 µg	267.00 USD

RAP functions in ER maturation of lipoprotein receptor family members by acting as an antagonist. It blocks binding of PCSK9 to lipoprotein receptors and of all known ligands (including MMP-9 and apoE) to lipoprotein receptor-related protein 1 (LRP-1). Modulates amyloid deposition in mouse models of Alzheimer’s disease. Reduces endocytosis of prion protein (PrP^c) by neuronal cells.

Product Specification

Alternative Name:	LDL receptor associated protein, LRPAP1, LDL receptor-related protein-associated protein 1

MW:	~39kDa (SDS-PAGE)

Purity:	≥90% (SDS-PAGE)

Source/Host:	Produced in E. coli.

Application:	Binding studies, and testing in vivo and in cell culture.

Long Term Storage:	-80°C

Handling:	After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.

Background / Technical Information:	Please click here for the comprehensive product data sheet.