RAP (human) (recombinant) - Enzo Life Sciences

BML-SE552

Revised 01-Feb-10

RAP (human) (recombinant)
SYNONYMS	LDL Receptor Associated Protein (human) (recombinant) LRPAP1 (human) (recombinant) LDL Receptor-related Protein-associated Protein 1 (human) (recombinant)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Convertases / Related Products / Furin

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
BML-SE552-0100		100 µg	259.00 USD

Product Specification

MW:	~39kDa (SDS-PAGE)
SOURCE/HOST:	Produced in E. coli.
PURITY:	≥90% (SDS-PAGE)
APPLICATION:	Binding studies, and testing in vivo and in cell culture.
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-80°C
HANDLING:	After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.

Product Description

RAP functions in ER maturation of lipoprotein receptor family members by acting as an antagonist. It blocks binding of PCSK9 to lipoprotein receptors and of all known ligands (including MMP-9 and apoE) to lipoprotein receptor-related protein 1 (LRP-1). Modulates amyloid deposition in mouse models of Alzheimer’s disease. Reduces endocytosis of prion protein (PrP^c) by neuronal cells.

General Information