Angiopoietin-1 (human) (recombinant) - Enzo Life Sciences

© 2009 Enzo Life Sciences, Inc.

BML-SE549

Revised 01-Feb-10

Angiopoietin-1 (human) (recombinant)
PRODUCT LINE	Cancer
PRODUCT CATEGORY	Angiopoietins & Tie Receptors / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
BML-SE549-0025		25 µg	275.00 USD
BML-SE549-0100		100 µg	936.00 USD

Product Specification

MW:	~66 kDa
SOURCE/HOST:	Produced in Sf9 cells. Recombinant human glycosylated angiopoietin-1 (Ang1, Angpt1) (aa 21-496) with an N-terminal purification tag.

General Information

Angiopoietin-1 is secreted by endothelial and other cell types as oligomers into the extracellular matrix, where it can bind to and activate the receptor tyrosine kinase Tie2. This in turn leads to expression of MMPs and plasmin; alteration of adhesion molecule function; smooth muscle cell and neutrophil chemotaxis; and smooth muscle cell differentiation to endothelial cells; generally resulting in angiogenesis. Ang1/Tie2 dysregulation have been implicated in rheumatoid arthritis, asthma, diabetic complications, and cancer.
BACKGROUND/TECHNICAL INFORMATION
Please click here for the comprehensive product datasheet.

Further Categories Containing This Product:

Recombinant Proteins / Fusion Proteins

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