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Brain derived neurotrophic factor (human), (recombinant)

Trk ligand
 
BML-SE546-0001 1 µg 105.00 USD
 
BML-SE546-0005 5 µg 262.00 USD
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Product Specification

Alternative Name:BDNF
 
Source:Produced in E. coli.
 
UniProt ID:P23560
 
Formulation:Lyophilized from a 0.2µm sterile water solution.
 
Purity:≥97%
 
Application Notes:Can be used as growth and differentiation factor for neuronal cultures and for receptor binding studies.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Brain derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic growth factors and is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is also required for differentiation of cortical and hippocampal GABAergic interneurons and induces differentiation of dopaminergic neurons and survival of some neuronal cultures. BDNF is expressed as a larger pro form and is cleaved by proteases into its mature form: a 27 kDa dimer formed by two identical subunits.
 

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