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TIMP-1 (human neutrophils), (purified)

MMP inhibitor
 
BML-SE530-0005 5 µg 296.00 USD
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Product Specification

Alternative Name:Tissue inhibitor of metalloproteinases 1
 
Source:Isolated from human neutrophils.
 
UniProt ID:P01033
 
Formulation:Liquid. In 50mM Tris-HCl, pH 7, containing 0.2M NaCl, 5mM CaCl2, 1µM ZnCl2, 0.05% Brij-35, 0.05% sodium azide.
 
Application Notes:Can be used as MMP or ADAM inhibitor in vitro or in tissue culture and as positive control in antibody applications or reverse zymograms.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-20°C
 
Scientific Background:TIMP-1 inhibits most MMPs, displaying ki’s in the low nanomolar range, although it is not very effective against the MT-MMPs. It also can inhibit ADAMs such as ADAM10 and ADAMTS4. While it can inhibit angiogenesis, it can also promote cell growth.
 

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