HDAC6 (human), (recombinant) (His-tag)

Highly active

Alternative Name:	Histone deacetylase 6, HDAC 6

MW:	131 kDa

Biological Activity:	Active with various fluorogenic peptide substrates, including Fluor de Lys™ substrate (Prod. No. BML-KI104) and Fluor de Lys™-SIRT1 (p53 379-382, K(Ac)382; Prod. No. BML-KI177).

Source/Host:	Produced in insect cells.

Long Term Storage:	-80°C

Miscellaneous/General:	HDAC6 is a class II HDAC, a group defined by its member’s homology to the yeast HDAC HDA1. It is unique among human HDACs in that it contains two full deacetylase domains. A tubulin deacetylase, HDAC6 may act to promote autophagic clearing of huntingtin aggregates and retard HIV1 infection, but also to promote invasive motility in tumor cells.

Background / Technical Information:	Please click here for the comprehensive product datasheet.