Proteinase 3 (human neutrophils)

Alternative Name:	PR3, Myeloblastin, Wegener's autoantigen

MW:	29 kDa

Source/Host:	Isolated from human sputum neutrophils.

Long Term Storage:	-20°C

Miscellaneous/General:	Proteinase 3 is a neutral serine protease located in neutrophil azurophil granules. It is closely related to neutrophil elastase and can cleave elastin. PR3 is involved in diseases such as Wegener’s granulomatosis, emphysema, vasculitis, and other inflammatory diseases.

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