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 United States

14-3-3ζ (human), (recombinant) (His-tag)

 
BML-SE485-0100 100 µg 237.00 USD
 

Product Specification

MW:~30 kDa
 
Purity:>90% (SDS-PAGE)
 
Source/Host:Produced in E. coli. Human 14-3-3ζ is fused at the C-terminus to a His-tag.
 
Application:Drug screening, protein-protein interaction studies, gel overlays.
 
Long Term Storage:-80°C
 
Miscellaneous/General:14-3-3 proteins are dimeric phosphoserine/phosphothreonine binding proteins, which have been shown to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation state and stability, transcription, metabolism, and malignant transformation. 14-3-3ζ has been shown to be present in brain amyloid plaques. It has also been hypothesized that 14-3-3ζ is recruited by cells to form protein aggregates with misfolded proteins in order to protect the cell against toxicity.
 
Background / Technical Information:Please click here for the comprehensive product datasheet.
 

General Literature References

C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3: T. Schwarz, et al.; BBRC 394, 890 (2010), Abstract;

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