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MKP-5 (human), (recombinant) (His-tag)

 
BML-SE467-0100 100 µg 387.00 USD
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Product Specification

Alternative Name:MAP kinase phosphatase 5, DUSP10, Dual specificity protein phosphatase 10
 
MW:53 kDa
 
Source:Produced in Sf9 insect cells. Recombinant human MKP-5 fused at the N-terminus to a His-tag. Produced in a baculovirus expression system.
 
UniProt ID:Q9Y6W6
 
Gene/Protein Identifier:NM_007207 (RefSeq)
 
Formulation:Liquid. In 20mM TRIS/HCl, pH 8.0, 200mM NaCl, 5mM DTT, 0.1 % Tween-20, 10% glycerol.
 
Purity Detail:Partially purified by single-step affinity chromatography and gel filtration.
 
Specific Activity:≥50 U/mg assayed by 3-O-methyl fluorescein phosphate (OMFP) hydrolysis at pH 8.2, 30°C. One unit is equal to 1 nmole phosphate hydrolyzed from OMFP per minute.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:MKP-5 (DUSP10) is a member of a group of dual specificity phosphatases which negatively regulate MAP kinases, dephosphorylating both the phosphotyrosine and phosphothreonine in the pTXpY activation loop motif. MKP5 has a principal function in both innate and adaptive immune responses.
 
BML-SE467 SDS-PAGE
SDS-PAGE Analysis. Lane 1: MW Marker, Lane 2: 1.0µg of purified MKP-5 (human) (recombinant) (His-tag).
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BML-SE467 SDS-PAGE

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