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PLK1 (human), (recombinant) (His-tag)

 
BML-SE466-0005 5 µg 256.00 USD
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Product Specification

Alternative Name:Polo-like kinase 1, STPK13, Serine/threonine protein kinase 13
 
MW:70 kDa
 
Source:Produced in insect cells. Full length active PLK1 is fused at the N-terminus to a His-tag.
 
UniProt ID:P53350
 
Application Notes:Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:PLK localizes to the mitotic spindle and microinjection of PLK into quiescent NIH 3T3 cells induces them to enter mitosis. PLK1 is elevated in many types of cancer and when depleted by siRNA, cell proliferation is inhibited and viability decreased.
 

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