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MKP-2 (human), (recombinant)

BML-SE462-0100 100 µg 419.00 USD
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Product Specification

Alternative Name:MAP kinase phosphatase 2, DUSP4, Dual specificity protein phosphatase 4, HVH2
MW:43 kDa
Source:Produced in Sf9 insect cells. Recombinant human MKP-2 fused at the N-terminus to a His-tag. Produced in a baculovirus expression system.
UniProt ID:Q13115
Gene/Protein Identifier:NM_001394 (RefSeq)
Formulation:Liquid. In 20mM TRIS/HCl, pH 8.0, 200mM NaCl, 5mM DTT, 0.1 % Tween-20, 10% glycerol.
Purity Detail:Partially purified by single-step affinity chromatography and gel filtration.
Specific Activity:≥60 U/mg assayed by 3-O-methyl fluorescein phosphate (OMFP) hydrolysis at pH 8.2, 30°C. One unit is equal to 1 nmole phosphate hydrolyzed from OMFP per minute.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:MKP-2 (DUSP4) is a member of a group of dual specificity phosphatases which negatively regulate MAP kinases, dephosphorylating both the phosphotyrosine and phosphothreonine in the pTXpY activation loop motif.

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