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FAK (human), (recombinant) (His-tag)

 
BML-SE448-0010 10 µg 371.00 USD
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Product Specification

Alternative Name:Focal adhesion kinase
 
MW:36 kDa
 
Source:Produced in insect cells. Active FAK (aa 411-686).
 
UniProt ID:Q05397
 
Formulation:Liquid. In 25 mM Tris-HCl, pH 8.0, containing 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
 
Application Notes:Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:FAK is involved in cell motility and it concentrates in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents such as fibronectin. It is also a major target for the tyrosine kinase Src and its deletion can block tumor formation and progression.
 

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