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Sphingosine kinase 2 (human), (recombinant) (His-tag)

BML-SE425-0010 10 µg 525.00 USD
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Product Specification

MW:70 kDa
Source:Produced in insect cells. Full length human SPHK2 is fused at the N-terminus to a His-tag. Produced in a baculovirus expression system.
UniProt ID:Q9NRA0
Formulation:Liquid. In 40mM Tris-HCl pH 8.0, 110 mM NaCl, 2/2 mM KCl, 3 mM DTT, 25 mM imidazole, and 20% glycerol.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:SPHK2 is one of two enzymes that can convert sphingosine to sphingosine-1-phosphate. SPHK2 has 45% identity and 80% similarity with SPHK1 and shares two large conserved regions. However, SPHK2 contains two extra domains, one internal and one at the N-terminus. SPHK2 is predominantly expressed in liver and heart.

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