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FAP (human), (recombinant) (His-tag)

 
BML-SE409-0010 10 µg 514.00 USD
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Product Specification

Alternative Name:Fibroblast activation protein α, Seprase, Surface expressed protease, APCE, Antiplasmin cleaving enzyme
 
MW:85.5 kDa
 
Source:Produced in a baculovirus expression system. Active recombinant human FAP (aa 29-760), representing a naturally-occurring cleaved (soluble) form fused at the C-terminus to a His-tag.
 
UniProt ID:Q12884
 
Formulation:Liquid. In 40mM TRIS-HCl, pH 8.0, containing 110mM NaCl, 2.2mM KCl, 200mM imidazole, 20% glycerol and 3mM DTT.
 
Application Notes:Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:FAP is a homodimeric serine prolyl peptidase that digests gelatin, collagen, and α2-antiplasmin. Due to its implication in cancer and blood disorders, it is a target for drug discovery. In addition, because this enzyme is related to DPPIV, it is useful for specificity screening of DPPIV inhibitors.
 

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