Aurora A (human), (recombinant) (His-tag)

MW:	50kDa

Source/Host:	Human recombinant aurora A kinase (aa 2-403) is fused at the N-terminus to a His-tag.

Application:	Kinetic studies and drug discovery.

Long Term Storage:	-80°C

Miscellaneous/General:	Aurora kinases control chromatid segregation and their expression is elevated in many human cancers making them targets of interest of anti-cancer therapeutics. Ectopic overexpression of aurora kinase A in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.

Background / Technical Information:	Please click here for the comprehensive product datasheet.