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Thrombin (human plasma), (purified)

 
BML-SE363-1000 1000 U 403.00 USD
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Product Specification

MW:37 kDa
 
Source:Isolated from human plasma as prothrombin, and activated with Factor Xa, Factor Va, phospholipids, and calcium to yield a-thrombin.
 
UniProt ID:P00734
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:Thrombin (factor IIa) is a serine endopeptidase comprising a light and a heavy chain, the latter being the catalytic subunit. Thrombin is a necessary component of the clotting cascade, and is important in cardiovascular research and drug development, and may play a role in Alzheimer’s disease as well.
 

Product Literature References

Release of platelet-derived sphingosine-1-phosphate involves multidrug resistance protein 4 (MRP4/ABCC4) and is inhibited by statins: K. Vogt, et al.; Thromb. Haemost. 118, 132 (2018), Abstract;
Multiple modes of capillary electrophoresis applied in peptide nucleic acid related study: X. Wang, et al.; J. Chromatogr. A. 1501, 161 (2017), Abstract;

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